The SARS-CoV-2 virus would never have spread in pandemic fashion, and probably would not have spread at all, if most or all of the population had at least the 50 ng/mL (125 nmol/L = 1 part in 20,000,000 by mass) circulating 25-hydroxyvitamin D which the immune system needs. Please see the research cited and discussed at https://vitamindstopscovid.info/00-evi/.
25-hydroxyvitamin D is made, primarily in the liver, by hydroxylating vitamin D3 cholecalciferol. This is measured in "vitamin D" blood tests. Neither vitamin D3 nor 25-hydroxyvitamin D are hormones. They are not signaling molecules. They are separate compounds with different roles in the body. Doctors tend to refer to them both as "vitamin D", along with 1,25-dihydroxyvitamin D calcitriol, but these three compounds have very different functions. Only cholecalciferol is a vitamin.
The kidneys can perform their role in regulating calcium-phosphate-bone metabolism with about 20 ng/mL (50 nmol/L) circulating 25-hydroxyvitamin D, which is what government recommended vitamin D3 supplemental quantities, such as 1000 IU (25 micrograms) per day or less are intended to attain.
However, many types of immune cell need 50 ng/mL in the bloodstream so it diffused into their cell bodies sufficiently to supply each individual cell's intracrine and paracrine signaling systems. These work entirely within the cell (intracrine) and to nearby cells (paracrine), typically of different types. These signaling systems are crucial to the cells' ability to respond to their changing circumstances. They are not related to hormonal (endocrine) signaling. These signaling systems are not affected by, and do not significantly affect, the very low level of hormonal calcitriol (~~0.05 to 0.1 ng/mL) the kidneys maintain in the bloodstream.
To attain the 50 ng/mL circulating 25-hydroxyvitamin D we need to be healthy, for 70 kg 154 lb body weight without obesity, it is generally necessary to supplement 125 micrograms of vitamin D3 a day, on average. This is 5000 IU, which sounds like a lot. However, it is a gram ever 22 years - and pharma-grade vitamin D3 costs about USD$2.50 a gram ex-factory.
About a tonne a day of vitamin D3 would supply all of humanity. At current prices this would cost about USD$1 billion a year, ex-factory.
There is very little vitamin D in food, including food fortified with vitamin D3 or the less effective vitamin D2. Ultraviolet B ca. 297 nanometre wavelength can produce plenty of vitamin D3 in ideally white skin, by breaking a bond in one of the carbon rings of 7-dehydrocholesterol. However, far from the equator, such UV-B is only available naturally in the middle of cloud-free summer days, without glass, clothing or sunscreen. Such UVB always damages DNA and so raises the risk of skin cancer.
The elderly, those with black or brown skin, and/or sun-avoidant lifestyles are particularly at risk of low 25-hydroxyvitamin D levels. This alone would explain a large proportion of the well-known health disparities suffered by African Americans relative to those with less melanized skin.
The proper amount of vitamin D3 to supplement to attain at least the required 50 ng/mL circulating 25-hydroxyvitamin D, without risk of toxicity and without the need for blood tests or medical monitoring, depends on body weight: 70 to 90 IU per day per kilogram. Higher ratios are needed for those suffering from obesity, since obesity reduces the rate of hydroxylation in the liver and the excess adipose tissue absorbs both vitamin D3 and 25-hydroxyvitamin D: https://vitamindstopscovid.info/00-evi/#obesity-deficit.
These ratios, recommended by New Jersey based Professor of Medicine Sunil Wimalawansa have been most recently published in in "Integrating Endocrine, Genomic, and Extra-Skeletal Benefits of Vitamin D into National and Regional Clinical Guidelines", Nutrients 2024-11-20 https://www.mdpi.com/2072-6643/16/22/3969 co-authored with another professor of medicine Scott T. Weiss and professor of pediatrics Bruce W. Hollis. All three have been researching vitamin D for decades.
The mainstream medical system is uninterested in nutritional supplements, especially proper vitamin D3 supplementation. This is partly due to wariness about over-hyped supplements, but it goes far beyond reason. There's a great deal of research on higher 25-hydroxyvitamin D levels reducing the risk of cancer and infectious diseases. Likewise pre-eclampsia pre-term birth and autism, ADHD and mental retardation in the children: https://vitamindstopscovid.info/00-evi/#3.2. Likewise neurodegeneration - Alzheimer's disease, Parkinson's disease, dementia with Lewy bodies, multiple system atrophy etc.: https://vitamindstopscovid.info/00-evi/#3.3.
However, most doctors know little or nothing about it since most doctors don't talk about it. Most are uninterested and cannot believe that something so simple could be so important. Immunologists have generally never heard of 25-hydroxyvitamin D -> calcitriol intracrine and paracrine signaling. These have only been elucidated in the last 15 years or so and there is no peer-reviewed tutorial explaining them. They are not complex: https://vitamindstopscovid.info/02-intracrine/.
The NYT played a significant role in this, with a hit-piece on the world's foremost vitamin D researcher, Prof, Michael Holick: Liz Szabo, 2028-08-18"Vitamin D, the Sunshine Supplement, Has Shadowy Money Behind It: The doctor most responsible for creating a billion-dollar juggernaut has received hundreds of thousands of dollars from the vitamin D industry."
In the early 2020s I recall that this article, which was then not behind a paywall, was the first item shown by Google's search engine for "vitamin D".
I have it from the Horse’s Mouth that the content of this op-ed, like other columns by Zeynep Tupekci, was cribbed from research by her wasband of 20 years past. The wasband is a courageous journalist, now ousted from the mainstream, who speaks truth to power and has paid a price. Tupekci repackages his research with a spin that makes it an appropriate limited hang-out for what is left of the Liberal Press. This is a window into the state of our controlled media.
While we're all understandably concerned about having our digital footprints used against us in the Cancellation Court (of Public Opinion), on a positive side, we can use the same tools to make it clear how much our "betters" either were absolute crap at their journalism (that's the nice interpretation) or were downright misleading. Either way, though we don't have the power to fire them, we do have the power to disinvest any trust we might have once placed in them, and give our attention to media figures, such as Madhava, whio have a proven track record of getting things right.
"How Scientists Could Stop the Next Pandemic Before It Starts" is the title of the missing NY Times article from April 21, 2020. It is still available on the paper's site, but the URL is actually https://www.nytimes.com/2020/04/21/magazine/pandemic-vaccine.html.
We are just about to start over-the-counter sales of ivermectin in Arkansas. (YAY!) The bill is on the governor's desk, awaiting her signature. I read that it had passed the state senate in an article written by a total twit shitlib employed by Arkansas NPR who thought it was just awful that such a thing would happen. She railed about the danger of people taking TOO MUCH ivermectin. I wrote to her and told her how brainwashed she was by the corporate media, but surprise, surprise, didn't hear back from her.
How can ANYONE ever trust any "public official" at all, about anything, the fraud about "covid" is too huge, I for one citizen here, do NOT trust the politicians to get anything right.
Martin has quoted Daszak as saying: “We need to increase the public understanding of the need for medical countermeasure, such as a pan-coronavirus vaccine. A key driver is the media and the economics will follow the hype. We need to use that hype to our advantage to get to the real issues. Investors will respond when they see profit at the end of the process.”
Bunch of real chicken shits at the nyt
🏆
Hilarious! Thanks for the belly laugh!!
Great set of historical headlines too. It's too rich. 🤣🤣🤣
Your headline is the understatement of the century, Madhava!
I could sense the sarcasm from a country mile away, lol
Good. The last time I wrote something satirical a hundred people unsubscribed
Madhava Setty— good one. I have nothing good to say about the NYT.
Funny! It’s a great summary of the hell we lived through and brilliant to have the headlines that misled. 🙏
The NYT is nothing more than a leftist criminal propaganda organization and should be treated as such 😡
Conservative Momma explains The Greater Good: https://x.com/conmomma/status/1451253296132329499.
The SARS-CoV-2 virus would never have spread in pandemic fashion, and probably would not have spread at all, if most or all of the population had at least the 50 ng/mL (125 nmol/L = 1 part in 20,000,000 by mass) circulating 25-hydroxyvitamin D which the immune system needs. Please see the research cited and discussed at https://vitamindstopscovid.info/00-evi/.
25-hydroxyvitamin D is made, primarily in the liver, by hydroxylating vitamin D3 cholecalciferol. This is measured in "vitamin D" blood tests. Neither vitamin D3 nor 25-hydroxyvitamin D are hormones. They are not signaling molecules. They are separate compounds with different roles in the body. Doctors tend to refer to them both as "vitamin D", along with 1,25-dihydroxyvitamin D calcitriol, but these three compounds have very different functions. Only cholecalciferol is a vitamin.
The kidneys can perform their role in regulating calcium-phosphate-bone metabolism with about 20 ng/mL (50 nmol/L) circulating 25-hydroxyvitamin D, which is what government recommended vitamin D3 supplemental quantities, such as 1000 IU (25 micrograms) per day or less are intended to attain.
However, many types of immune cell need 50 ng/mL in the bloodstream so it diffused into their cell bodies sufficiently to supply each individual cell's intracrine and paracrine signaling systems. These work entirely within the cell (intracrine) and to nearby cells (paracrine), typically of different types. These signaling systems are crucial to the cells' ability to respond to their changing circumstances. They are not related to hormonal (endocrine) signaling. These signaling systems are not affected by, and do not significantly affect, the very low level of hormonal calcitriol (~~0.05 to 0.1 ng/mL) the kidneys maintain in the bloodstream.
To attain the 50 ng/mL circulating 25-hydroxyvitamin D we need to be healthy, for 70 kg 154 lb body weight without obesity, it is generally necessary to supplement 125 micrograms of vitamin D3 a day, on average. This is 5000 IU, which sounds like a lot. However, it is a gram ever 22 years - and pharma-grade vitamin D3 costs about USD$2.50 a gram ex-factory.
About a tonne a day of vitamin D3 would supply all of humanity. At current prices this would cost about USD$1 billion a year, ex-factory.
There is very little vitamin D in food, including food fortified with vitamin D3 or the less effective vitamin D2. Ultraviolet B ca. 297 nanometre wavelength can produce plenty of vitamin D3 in ideally white skin, by breaking a bond in one of the carbon rings of 7-dehydrocholesterol. However, far from the equator, such UV-B is only available naturally in the middle of cloud-free summer days, without glass, clothing or sunscreen. Such UVB always damages DNA and so raises the risk of skin cancer.
The elderly, those with black or brown skin, and/or sun-avoidant lifestyles are particularly at risk of low 25-hydroxyvitamin D levels. This alone would explain a large proportion of the well-known health disparities suffered by African Americans relative to those with less melanized skin.
The proper amount of vitamin D3 to supplement to attain at least the required 50 ng/mL circulating 25-hydroxyvitamin D, without risk of toxicity and without the need for blood tests or medical monitoring, depends on body weight: 70 to 90 IU per day per kilogram. Higher ratios are needed for those suffering from obesity, since obesity reduces the rate of hydroxylation in the liver and the excess adipose tissue absorbs both vitamin D3 and 25-hydroxyvitamin D: https://vitamindstopscovid.info/00-evi/#obesity-deficit.
These ratios, recommended by New Jersey based Professor of Medicine Sunil Wimalawansa have been most recently published in in "Integrating Endocrine, Genomic, and Extra-Skeletal Benefits of Vitamin D into National and Regional Clinical Guidelines", Nutrients 2024-11-20 https://www.mdpi.com/2072-6643/16/22/3969 co-authored with another professor of medicine Scott T. Weiss and professor of pediatrics Bruce W. Hollis. All three have been researching vitamin D for decades.
An easier to read guide to these recommendations is at: https://vitamindstopscovid.info/00-evi/#00-how-much.
The mainstream medical system is uninterested in nutritional supplements, especially proper vitamin D3 supplementation. This is partly due to wariness about over-hyped supplements, but it goes far beyond reason. There's a great deal of research on higher 25-hydroxyvitamin D levels reducing the risk of cancer and infectious diseases. Likewise pre-eclampsia pre-term birth and autism, ADHD and mental retardation in the children: https://vitamindstopscovid.info/00-evi/#3.2. Likewise neurodegeneration - Alzheimer's disease, Parkinson's disease, dementia with Lewy bodies, multiple system atrophy etc.: https://vitamindstopscovid.info/00-evi/#3.3.
However, most doctors know little or nothing about it since most doctors don't talk about it. Most are uninterested and cannot believe that something so simple could be so important. Immunologists have generally never heard of 25-hydroxyvitamin D -> calcitriol intracrine and paracrine signaling. These have only been elucidated in the last 15 years or so and there is no peer-reviewed tutorial explaining them. They are not complex: https://vitamindstopscovid.info/02-intracrine/.
There has long been a campaign of ignoring and maligning vitamin D research. See vitamin D researcher Bill Grant's 2018 article "Vitamin D acceptance delayed by Big Pharma following the Disinformation Playbook" https:// orthomolecular.org/resources/omns/v14n22.shtml. See also Dr Pierre Kory telling Tucker Carlson that "They [the pharmaceutical industry and too many doctors] are "scared of vitamin D": https:// twitter.com/TuckerCarlson/status/1768033041568727391 (transcript https:// nutritionmatters.substack.com/p/dr-pierre-kory-talks- with-tucker).
The NYT played a significant role in this, with a hit-piece on the world's foremost vitamin D researcher, Prof, Michael Holick: Liz Szabo, 2028-08-18"Vitamin D, the Sunshine Supplement, Has Shadowy Money Behind It: The doctor most responsible for creating a billion-dollar juggernaut has received hundreds of thousands of dollars from the vitamin D industry."
In the early 2020s I recall that this article, which was then not behind a paywall, was the first item shown by Google's search engine for "vitamin D".
The New York Times is harming and killing people.
I have it from the Horse’s Mouth that the content of this op-ed, like other columns by Zeynep Tupekci, was cribbed from research by her wasband of 20 years past. The wasband is a courageous journalist, now ousted from the mainstream, who speaks truth to power and has paid a price. Tupekci repackages his research with a spin that makes it an appropriate limited hang-out for what is left of the Liberal Press. This is a window into the state of our controlled media.
“We were misled…” “Mistakes were made…” The Fonz had trouble saying it too!
https://youtu.be/uwkU8-d1gIk?si=6C5o6h7HHCZvofQ0
While we're all understandably concerned about having our digital footprints used against us in the Cancellation Court (of Public Opinion), on a positive side, we can use the same tools to make it clear how much our "betters" either were absolute crap at their journalism (that's the nice interpretation) or were downright misleading. Either way, though we don't have the power to fire them, we do have the power to disinvest any trust we might have once placed in them, and give our attention to media figures, such as Madhava, whio have a proven track record of getting things right.
"How Scientists Could Stop the Next Pandemic Before It Starts" is the title of the missing NY Times article from April 21, 2020. It is still available on the paper's site, but the URL is actually https://www.nytimes.com/2020/04/21/magazine/pandemic-vaccine.html.
We are just about to start over-the-counter sales of ivermectin in Arkansas. (YAY!) The bill is on the governor's desk, awaiting her signature. I read that it had passed the state senate in an article written by a total twit shitlib employed by Arkansas NPR who thought it was just awful that such a thing would happen. She railed about the danger of people taking TOO MUCH ivermectin. I wrote to her and told her how brainwashed she was by the corporate media, but surprise, surprise, didn't hear back from her.
How can ANYONE ever trust any "public official" at all, about anything, the fraud about "covid" is too huge, I for one citizen here, do NOT trust the politicians to get anything right.
Who Believes This Shit?!?!
It's great that we can all have a chuckle about murder.
You mean this Peter Daszak? https://corruption.news/2021-09-28-daszak-plotting-to-make-everyone-accept-vaccine.html#
Martin has quoted Daszak as saying: “We need to increase the public understanding of the need for medical countermeasure, such as a pan-coronavirus vaccine. A key driver is the media and the economics will follow the hype. We need to use that hype to our advantage to get to the real issues. Investors will respond when they see profit at the end of the process.”